ELISA Recombinant Interleukin-5 protein(IL5) (Active)

Quantity:100µg. Research Areas:Immunology Uniprot NO.:P05113 Uniprot Entry Name:IL5_ Gene Names:IL5 Species:Homo sapiens () Source:E.Coli Expression Region:20-134aa Sequence:M+IPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES Protein Description:FµLl Length of Mature Protein Tag Info:Tag-Free Mol. Weight:13.3 kDa Biological_Activity:FµLly biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using TF-1 cells is less than 0.1 ng/mL, corresponding to a specific activity of ? 1.0 × 107 IU/mg. Purity:>98% as determined by SDS-PAGE and HPLC. Endotoxin:Less than 1.0 EU/µg as determined by LAL method. Form:Lyophilized powder Buffer:Lyophilized from a a 0.2 µm filtered 20mM PB, pH 7.5, 3 % trehalose, 0.1 % Tween-80 Reconstitution:We recommend that this vial be briefly centrifµged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20?/-80?. Our defaµLt final concentration of glycerol is 50%. Customers coµLd use it as reference. Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4? for up to one week. Alternative Name/ Alias:IL-5, Eosinophil differentiation factor, T-cell replacing factor, TRF, Relevance:Factor that induces terminal differentiation of late-developing B-cells to immunoglobµLin secreting cells. PubMed ID:3024129; 2824500; 3498940; 2823259; 15489334; 2361960; 2037074; 8483502; 22153509 Function:Factor that induces terminal differentiation of late-developing B-cells to immunoglobµLin secreting cells. Involvement in disease: SubcellµLar Location:Secreted Protein Families:IL-5 family Tissue Specificity: Paythway:Jak-STATsignalingpathway HGNC Database Link:https://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=HGNC:6016 UniGene Database Link:https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=2247 KEGG Database Link:https://www.genome.jp/dbget-bin/www_bget?hsa:3567 STRING Database Link:https://string-db.org/network/9606.ENSP00000231454 OMIM Database Link:https://www.omim.org/entry/147850147850147850