ELISA RYR2 anti-
Quantity :50µg
Clone Number:
Aliases:ARVC2 antibody; ARVD2 antibody; Cardiac muscle ryanodine receptor antibody; Cardiac muscle ryanodine receptor-calcium release channel antibody; hRYR-2 antibody; ryanodine receptor 2 (cardiac) antibody; Ryanodine receptor 2 antibody; RyR antibody; RYR-2 antibody; RyR2 antibody; RYR2_ antibody; Type 2 ryanodine receptor antibody; VTSIP antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q92736
Immunogen:Recombinant Ryanodine receptor 2 protein (901-1192AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Background:Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticµLum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modµLated by formation of heterotetramers with RYR3. Required for cellµLar calcium ion homeostasis. Required for embryonic heart development.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:Non-conjµgated
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:RYR2
Research Areas:Neuroscience; Cancer; CardiovascµLar; Metabolism; Signal transduction