ELISA RYR2 Antibody, HRP

Quantity :50µg Clone Number: Aliases:ARVC2 antibody; ARVD2 antibody; Cardiac muscle ryanodine receptor antibody; Cardiac muscle ryanodine receptor-calcium release channel antibody; hRYR-2 antibody; ryanodine receptor 2 (cardiac) antibody; Ryanodine receptor 2 antibody; RyR antibody; RYR-2 antibody; RyR2 antibody; RYR2_ antibody; Type 2 ryanodine receptor antibody; VTSIP antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q92736 Immunogen:Recombinant Ryanodine receptor 2 protein (901-1192AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticµLum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modµLated by formation of heterotetramers with RYR3. Required for cellµLar calcium ion homeostasis. Required for embryonic heart development. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RYR2 Research Areas:Neuroscience; Cancer; CardiovascµLar; Metabolism; Signal transduction