Motolimod (VTX-2337)

Motolimod (VTX-2337) 

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IKAP Antibody

2337-01mg 0.1 mg
EUR 436.42
Description: IKAP Antibody: IKAP was initially identified as a scaffold protein of the IκB kinase complex that could bind to IKKα, IKKβ, NF-κB, and the NF-κB-inducing kinase (NIK), although later evidence has cast doubt on this. More recent reports show that mutations in IKAP such as a frameshift leading to a truncated protein or a missense mutation that leads to defective phosphorylation are responsible for the autosomal recessive genetic disease familial dysautonomia (FD). Reports indicating that it forms part of the RNA polymerase II transcription elongation complex suggest that this disease may be due to compromised transcription elongation. More recently, it was shown that IKAP associates with c-Jun N-terminal kinase (JNK) and could specifically enhance JNK activation induced by the upstream JNK activators MEKK1 and ASK1, indicating another possible cause for FD.

ASXL2 Blocking Peptide

33R-2337 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of ASXL2 antibody, catalog no. 70R-3526

PAK1/PAK2/PAK3 antibody

20R-2337 50 ug
EUR 281
Description: Rabbit polyclonal PAK1/PAK2/PAK3 antibody

GSTO2 antibody

70R-2337 50 ug
EUR 467
Description: Rabbit polyclonal GSTO2 antibody raised against the N terminal of GSTO2

FGF2 protein

30R-2337 50 ug
EUR 352
Description: Purified recombinant Human FGF2 protein

DTSSP Crosslinker

EUR 468

DTSSP Crosslinker

EUR 156

DTSSP Crosslinker

2337-500 Ask for price

Human Plakophilin 2 (PKP2)ELISA kit

201-12-2337 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Anti-EGFR (Modotuximab)-SPDB-DM4 ADC

ADC-W-2337 1mg Ask for price
Description: This ADC product is comprised of an anti-EGFR monoclonal antibody conjugated via a SPDB linker to DM4

Motolimod (VTX-2337)