Motolimod (VTX-2337)

Description: IKAP Antibody: IKAP was initially identified as a scaffold protein of the IκB kinase complex that could bind to IKKα, IKKβ, NF-κB, and the NF-κB-inducing kinase (NIK), although later evidence has cast doubt on this. More recent reports show that mutations in IKAP such as a frameshift leading to a truncated protein or a missense mutation that leads to defective phosphorylation are responsible for the autosomal recessive genetic disease familial dysautonomia (FD). Reports indicating that it forms part of the RNA polymerase II transcription elongation complex suggest that this disease may be due to compromised transcription elongation. More recently, it was shown that IKAP associates with c-Jun N-terminal kinase (JNK) and could specifically enhance JNK activation induced by the upstream JNK activators MEKK1 and ASK1, indicating another possible cause for FD.

Description: A synthetic peptide for use as a blocking control in assays to test for specificity of ASXL2 antibody, catalog no. 70R-3526

Description: Rabbit polyclonal PAK1/PAK2/PAK3 antibody

Description: Rabbit polyclonal GSTO2 antibody raised against the N terminal of GSTO2

Description: Purified recombinant Human FGF2 protein

Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Description: This ADC product is comprised of an anti-EGFR monoclonal antibody conjugated via a SPDB linker to DM4